TIC10

Size

£153.00

SKU:: 10-4090
Additional Names:: Dordaviprone|ONC201
Physical State:: Solid
Molecular Weight:: 386.49
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1616632-77-9
Immunogen:: Protease
Extra Details:: TIC10 is novel anti-cancer compound that acts via early-stage integrated stress response activation leading to selective cancer cell death.1-3 TIC10 potently activates mitochondrial caseinolytic protease P (ClpP) causing eIF2A Alpha-independent induction of ATF4 and Akt/ERK/Foxo3a/DR5/TRAIL-dependent apoptosis.4 Clinical ly useful anticancer agent.