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10-4052

Raltitrexed

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£149.00

SKU:
10-4052
Additional Names:
ICI D 1694|ZD1694
Physical State:
Solid
Molecular Weight:
458.49
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
112887-68-0
Immunogen:
DNA|Protein methyltransferase
Extra Details:
Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased AB Beta aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer's disease.3
Shipping Conditions:
Ambient