GSK620

Size

£151.00

SKU:: 10-4047
Physical State:: Solid
Molecular Weight:: 325.37
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 2088410-46-0
Immunogen:: Bromodomain
Extra Details:: BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).