10-4021
EED-226
Size
£163.00
- SKU:
- 10-4021
- Physical State:
- Solid
- Molecular Weight:
- 369.40
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2083627-02-3
- Immunogen:
- Protein methyltransferase
- Extra Details:
- EED-226 is a potent (IC50 = 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repressive complex 2 (PRC2).1,2 It caused drastic proliferation inhibition in lymphoma cells with EZH2 mutations and caused shrinkage and slower tumor growth in mice using a subcutaneous xenograft model of Karpas422.
- Shipping Conditions:
- Ambient