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10-4019

SP2509

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£173.00

SKU:
10-4019
Additional Names:
HCI-2509
Physical State:
Solid
Molecular Weight:
437.9
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
1423715-09-6
Immunogen:
Protein demethylase
Extra Details:
Potent (IC50 = 13 nM) and reversible inhibitor of the histone demethylase LSD1 (KDM1A).1 It is inactive against the closely related flavin enzymes MAO A,B as well as lactate dehydrogenase, several CYP's and hERG. LSD1 regulates the balance between self-renewal and differentiation of stem cells and is highly expressed in various cancers.2-6 SP2509 promotes autophagy in neuroblastoma cells.7
Shipping Conditions:
Ambient