10-4018
A-196
Size
£168.00
- SKU:
- 10-4018
- Physical State:
- Solid
- Molecular Weight:
- 359.25
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1982372-88-2
- Immunogen:
- Protein methyltransferase
- Extra Details:
- A-196 (1982372-88-2) is a potent and selective (over 29 other methyltransferases) inhibitor of the protein lysine methyltransferases SUV420H1(IC50 = 25 nM) and SUV420H2 (IC50 = 144 nM). It substantially inhibited non-homologous end-joining (NHEJ)-directed DNA repair but not homology-directed repair(HDR) in cells treated with ionizing radiation. A-196 is active in cells and displayed no toxicity in several cell lines.
- Shipping Conditions:
- Ambient