Lomeguatrib

Size

£153.00

SKU:: 10-4017
Additional Names:: O6-(4-Bromothenyl)guanine
Physical State:: Solid
Molecular Weight:: 326.17
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 192441-08-0
Immunogen:: DNA|Methyltransferase|Nucleic acid methylation
Extra Details:: Lomeguatrib is a potent (IC50 = 9 nM) inhibitor of O6-Methylguanine-DNA Methyltransferase (MGMT), an important DNA repair protein.1 It is currently being investigated in cancers that have acquired resistant to the chemotherapeutic temozolomide2-5, as well as other chemotherapeutics6,7.