Anacardic acid

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£139.00

SKU:: 10-4015
Additional Names:: 6-PDSA|6-Pentadecylsalicylic acid
Physical State:: Solid
Molecular Weight:: 348.52
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 16611-84-0
Immunogen:: Acetyltransferase|Protease
Extra Details:: Anacardic acid is a natural product found in cashew nut oil. It is an inhibitor of the histone acetyltransferases p300 and PCAF (IC50's = 8.5 and 5.0 uM respectively).1 Anacardic acid sensitizes cancer cells to ionizing radiation2 and suppresses proteins involved in invasion and angiogenesis (Src/FAK/Rho GTPases3 and MMP's 2 (IC50 = 11.11 uM)4 and 9). It inhibits both inducible and constitutive NF-K KappaB activation.5