10-4011
Selinexor
Size
£163.00
- SKU:
- 10-4011
- Additional Names:
- KPT-330
- Physical State:
- Solid
- Molecular Weight:
- 443.31
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1393477-72-9
- Extra Details:
- Selinexor is a potent inhibitor of the nuclear export receptor, chromosome region maintenance 1 (CRM1; Exportin-1 (XPO1)). It exhibited potent growth suppression in various T-cell acute lymphoblastic leukemia (T-ALL) cells (IC50's = 34-203 nM)1 and pancreatic cancer cells (IC50 ~ 150 nM)2. Selinexor is being investigated as a possible chemotherapeutic in treating multiple types of cancer.3-8 Currently in clinical trials.
- Shipping Conditions:
- Ambient