10-3998
Thiothixene

Size
£149.00
- SKU:
- 10-3998
- Physical State:
- Solid
- Molecular Weight:
- 443.62
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 3313-26-6
- Immunogen:
- Dopamine|Serotonin
- Extra Details:
- Thiothixene is a clinically useful typical antipsychotic.1 It acts as an antagonist at multiple receptors including dopamine D2 and D3 (sub-nanomolar), histamine H1, serotonin 5-HT7, and A Alpha1/2-adrenergic. Thiothixene stimulates efferocytosis, the phagocytic removal of apoptotic cells by macrophages, via increased expression of the retinol-binding protein receptor Stra6L leading to arginase 1 production.2 A potential new use for an old drug to facilitate the removal of diseased tissue.
- Shipping Conditions:
- Ambient
