10-3992
Sibiriline
Size
POA
- SKU:
- 10-3992
- Physical State:
- Solid
- Molecular Weight:
- 210.24
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1346526-26-8
- Immunogen:
- Antioxidant
- Extra Details:
- Sibiriline is a novel dual inhibitor of necroptosis and ferroptosis.1,2 It prevents necroptosis via inhibition of RIPK1 (IC50 = 1.1 uM) and ferroptosis via inhibition of phospholipid peroxidation acting as a radical trapping antioxidant. Sibiriline displayed neuroprotective effects in a mouse model of Parkinson's disease.
- Shipping Conditions:
- Ambient