10-3971
SCR-1481B1
Size
£129.00
- SKU:
- 10-3971
- Additional Names:
- Metatinib tromethamine
- Physical State:
- Solid
- Molecular Weight:
- 821.12
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1174161-86-4
- Immunogen:
- Kinase
- Extra Details:
- SCR-1481B1 is an inhibitor of HGFR (Met) and VEGFR kinases.1 SCR-1481B1 potently suppresses gasdermin D-mediated pyroptosis via targeting of the oligomerization interface I.2 Active in vivo in a mouse model of sepsis. SCR-1481B1 acts synergistically with another gasdermin D inhibitor, Cefcapene pivoxil (Cat #10-3972), and a PD-L1 antibody to significantly enhance the antitumor activity of anti-PD-L1 therapy.
- Shipping Conditions:
- Ambient