10-3966
Helicase inhibitor (S)-27
Size
£177.00
- SKU:
- 10-3966
- Additional Names:
- Helicase inhibitor (S)-27
- Physical State:
- Solid
- Molecular Weight:
- 449.47
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 3058652-58-4
- Immunogen:
- DNA
- Extra Details:
- (S)-27 is a potent (pIC50(0 hr/4hr) = 5.4/7.5) inhibitor of WRN helicase. Inhibition is via covalent binding to WRN Cys727. (S)-27 inhibited (pIC50 = 5.0) the high microsatellite instability colon adenocarcinoma line SW48 (MSI-H).
- Shipping Conditions:
- Ambient