10-3936
EN450
Size
£177.00
- SKU:
- 10-3936
- Additional Names:
- N-[2-Chloro-5-(dimethylsulfamoyl)phenyl]prop-2-enamide
- Physical State:
- Solid
- Molecular Weight:
- 288.75
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 793719-01-4
- Immunogen:
- Molecular glue
- Extra Details:
- EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1
- Shipping Conditions:
- Ambient