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  2. Enzyme Inhibitors

10-3920

BIBR1532

Size

£158.00

SKU:
10-3920
Physical State:
Solid
Molecular Weight:
331.37
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
321674-73-1
Immunogen:
Telomerase|Transcription factor
Extra Details:
Non-competitive specific inhibitor of telomerase (IC50 = 93 nM), targeting telomerase reverse transcriptase (hTERT).1,2 Induces apoptosis in MCF-7 breast cancer cells and breast cancer stem cells3 and affected the epithelial mesenchymal transition in breast cancer stem cells4. BIBR1532 eliminated pancreatic stem cells via DNA damage and apoptosis in primary patient-derived samples.5 It significantly inhibited cell proliferation and induced apoptosis in acute myeloid leukemia stem cells.6
Shipping Conditions:
Ambient