10-3919
IMT1B
Size
£221.00
- SKU:
- 10-3919
- Additional Names:
- LDC203974
- Physical State:
- Solid
- Molecular Weight:
- 473.88
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2304621-06-3
- Immunogen:
- RNA
- Extra Details:
- IMT1B (2304621-06-3) is a specific inhibitor of mitochondrial DNA (mtDNA) transcription. It targets an allosteric binding site on human mitochondrial RNA polymerase leading to impairment of biogenesis of the oxidative phosphorylation (OXPHOS) system.1 IMT1B displayed efficacy in mice containing human A2780 or DLD-1 cancer cell xenografts. IC50 = 138 nM A2780 cancer cells.2
- Shipping Conditions:
- Ambient