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10-3912

DRP1 inhibitor 4a

Size

£177.00

SKU:
10-3912
Physical State:
Solid
Molecular Weight:
359.43
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
Extra Details:
DRP1 inhibitor 4a blocks (IC50 = 100 nM) the protein-protein interaction between dynamin related protein 1 (DRP1) and the mitochondrial membrane receptor MiD49 preventing mitochondrial fragmentation.1 It prevented roughly half of mitochondrial fragmentation in A549 cells caused by carbonylcyanide-3-chlorophenylhydrazone (CCCP).
Shipping Conditions:
Ambient