KL044

Size

£187.00

SKU:: 10-3911
Physical State:: Solid
Molecular Weight:: 359.81
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 1801856-93-8
Extra Details:: Potent stabilizer of the circadian clock protein cryptochrome (CRY).1 It lengthened the circadian period and repressed Per2 activity in reporter assays with 10-fold more potency than KL001 (Cat# 10-1411). KL044 inhibited melanogenesis and melanosome transport via suppression of the cAMP/PKA/CREB pathway.2