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10-3909

TH301

Size

£177.00

SKU:
10-3909
Physical State:
Solid
Molecular Weight:
485.98
Purity:
98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
450338-32-6
ABP:
No Import Docs
Extra Details:
TH301 is an isoform-selective stabilizer of the circadian clock protein CRY2. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. TH301 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.
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Ambient