10-3779
UPF-1069
Size
£153.00
- SKU:
- 10-3779
- Physical State:
- Solid
- Molecular Weight:
- 279.29
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1048371-03-4
- Immunogen:
- Kinase|PARP
- Extra Details:
- A selective PARP-2 inhibitor (IC50=0.3 uM and ~ 27-fold selective against PARP-1).1,2 Increases apoptosis in hippocampal slices but protects cortical cells in models of post-ischemic brain damage.3 Blocks the interaction between PARP-2 and FOXA1, attenuating androgen receptor-mediated gene expression and inhibiting androgen receptor-positive prostate cancer growth.4
- Shipping Conditions:
- Ambient