TG-100572 HCl

Size

£173.00

SKU:: 10-3778
Physical State:: Solid
Molecular Weight:: 512.44
Purity:: >98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 867331-64-4
Immunogen:: Kinase
Extra Details:: TG-100572 is a multi-targeted kinase inhibitor that inhibits selected receptor kinases and Src kinases. IC50s = 2, 7, 2, 16, 13 VEGFR1, VEGFR2, FGFR1, FGFR2 PDGFRB Beta and 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for Fgr, Fyn, Hck, Lck, Lyn, Src and Yes respectively.1 It suppresses choroidal neovascularization and retinal edema1. Blocks angiogenesis caused by HSV infection in the mouse eye.2 A prodrug strategy has been employed for topically applied AMD treatment.3