10-3652
SCR7 pyrazine
Size
£168.00
- SKU:
- 10-3652
- Additional Names:
- SCR7-G|SCR7-X
- Physical State:
- Solid
- Molecular Weight:
- 332.38
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 14892-97-8
- Immunogen:
- DNA
- Extra Details:
- SCR7 pyrazine enhances the efficiency of precise genome editing with CRISPR/Cas9 up to 19-fold via inhibition of nonhomologous end joining (NHEJ).1,2 May be employed in an optimized CRISPR/Cas9 method to target methylation in a site-specific manner enabling maintenance of gene silencing in vitro and in vivo.3 SCR7 pyrazine exhibits greater activity against DNA ligases I and III than DNA ligase IV.4 Induces cancer cell death via inhibition of NHEJ and potentiates the effect of double strand break-inducing therapeutic modalities.4,5
- Shipping Conditions:
- Ambient