10-3613
Santacruzamate A
Size
£145.00
- SKU:
- 10-3613
- Physical State:
- Solid
- Molecular Weight:
- 278.35
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1477949-42-0
- Immunogen:
- Protein deacetylase
- Extra Details:
- A highly potent and selective inhibitor of HDAC2 isolated from the Panamanian marine cyanobacterium cf. Symploca (IC50=0.119 and 434 nM for HDAC2 and HDAC6 respectively).1 Induces apoptosis and cancer cell death only in combination with other HDAC1 inhibitors.2 Potential therapeutic agent for breast cancer.3 Attenuates A fragment (A25-35)-induced toxicity in PC12 cells by enhancing ER stress tolerance.4 Ameliorates Alzheimer's disease-like pathology in mouse models.4
- Shipping Conditions:
- Ambient