Verteporfin

Size

£173.00

SKU:: 10-3487
Additional Names:: BPD-MA|CL 318,952
Physical State:: Solid
Molecular Weight:: 718.79
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 129497-78-5
Immunogen:: Transcription factor
Extra Details:: Verteporfin inhibits transcription by YAP/TAZ, IC50 = 2.5 uM, (via disruption of YAP-TEAD interaction) inhibiting autophagy and halting proliferation of cancer and cancer stem cell lines.1,2 Inhibits autophagosome formation.3 Reverses differentiation of Src-overexpressing embryonic stem cells.4 May be used to ablate unwanted neovasculature in the eye, esophageal mucosa, and elsewhere using light to create damaging free radicals.5