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10-3476

Autophinib

Size

£153.00

SKU:
10-3476
Physical State:
Solid
Molecular Weight:
346.73
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
1644443-47-9
Immunogen:
Kinase
Extra Details:
Inhibits autophagy induced by starvation or rapamycin by inhibiting the lipid kinase VPS34 (IC50=19 nM).1 Increased autophagy and apoptosis were rescued by autophinib in Per1-overexpressing oral squamous cell carcinoma cells.2 Autophinib has quickly become an important biochemical tool for inhibition of autophagy in a variety of cellular contexts.3-5
Shipping Conditions:
Ambient