10-3467
Piericidin A
Size
£144.00
- SKU:
- 10-3467
- Additional Names:
- AR-054|Piericidin A1|Shaoguanmycin B|SN 198E
- Physical State:
- Solid
- Molecular Weight:
- 415.57
- Purity:
- 94%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 2738-64-9
- Immunogen:
- Antibiotic|Energy production
- Extra Details:
- A potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxidoreductase (complex I).1 Piericidin A is a ubiquinone analog which binds to the ubiquinone binding site of the enzyme.2 It is an extremely useful tool for exploring the role of complex I in mitochondrial function in both normal and pathophysiology.3-5 Prevents upregulation of GRP78 and induces cell death in glucose-deprived, etoposide-resistant HT-29 cells (IC50=7.7 nM).6
- Shipping Conditions:
- Ambient