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10-3396

PCI-34051

Size

£158.00

SKU:
10-3396
Physical State:
Solid
Molecular Weight:
296.33
Purity:
>98%
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
950762-95-5
Immunogen:
Protein deacetylase
Extra Details:
PCI-34051 is a potent and selective HDAC8 inhibitor (IC50=10 nM) with greater than 200-fold selectivity over HDACs 1, 2, 3, 6, 10.1 Unlike broad-spectrum HDAC inhibitors, it does not cause detectable histone or tubulin acetylation.1 Studies employing PCI-34051 showed that HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine.2 It is a very useful tool for exploring the role of HDAC8 in cellular function.3-6
Shipping Conditions:
Ambient