10-3375
AC1903
Size
£168.00
- SKU:
- 10-3375
- Physical State:
- Solid
- Molecular Weight:
- 303.36
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 831234-13-0
- Immunogen:
- Ion channel
- Extra Details:
- A potent and selective TRPC5 blocker. Suppresses severe proteinuria and prevents podocyte loss in a transgenic rat model of focal segmental glomerulosclerosis. It also provided therapeutic benefit in a rat model of hypertensive proteineuric kidney disease. The use of this selective tool compound provided a mechanistic rationale for targeting TRPC5 channels in progressive chronic kidney diseases and paves the way for the discovery of new therapeutics. Active in vivo.
- Shipping Conditions:
- Ambient