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10-3346

CK-666

Size

£163.00

SKU:
10-3346
Physical State:
Solid
Molecular Weight:
296.34
Purity:
98%
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
442633-00-3
Immunogen:
Cytoskeleton
Extra Details:
A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 uM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.
Shipping Conditions:
Ambient