10-3220
Leu-Leu-OMe HBr
Size
£144.00
- SKU:
- 10-3220
- Additional Names:
- LLME
- Physical State:
- Solid
- Molecular Weight:
- 339.27
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 16689-14-8
- Immunogen:
- Lysosome
- Extra Details:
- Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
- Shipping Conditions:
- Ambient