10-3148
NSC59984
Size
£158.00
- SKU:
- 10-3148
- Physical State:
- Solid
- Molecular Weight:
- 265.27
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 803647-40-7
- Immunogen:
- Transcription factor
- Extra Details:
- p53 activator. Restores wild-type p53 signaling and depletes mutant p53 gain of function. Induces mutant p53 protein degradation via MDM2 and ubiquitin-proteasome pathway. Induces p73-dependent cell death in cancer cells without toxicity toward normal cells.1 Inhibition of p53-MDM2 interaction remains a viable strategy for cancer therapeutic development.2,3
- Shipping Conditions:
- Ambient