10-3141
ABT-263
Size
£158.00
- SKU:
- 10-3141
- Additional Names:
- Navitoclax
- Physical State:
- Solid
- Molecular Weight:
- 974.6
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 923564-51-6
- Immunogen:
- Bcl-2
- Extra Details:
- Potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials2. Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model3. A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner4.
- Shipping Conditions:
- Ambient