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10-3069

GW3965 HCl

Size

£153.00

SKU:
10-3069
Physical State:
Solid
Molecular Weight:
618.52
Purity:
>98%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
405911-17-3
Immunogen:
Transcription factor
Extra Details:
GW3965 is a potent and selective LXR agonist, activating human LXRA Alpha and B Beta in cell-based reporter gene assays (EC50=190 and 30 nM respectively).1 Since LXR is a master regulator of cholesterol and fatty acid metabolism, GW3965 exerts a variety of effects including antiatherosclerotic2, antiinflammatory3 as well as antinociceptive4 and alteration of fat tissue distribution5. Orally active.
Shipping Conditions:
Ambient