Flavopiridol HCl

Size

£149.00

SKU:: 10-3063
Additional Names:: Alvocidib|L 86-8275|NSC-649890
Physical State:: Solid
Molecular Weight:: 438.30
Purity:: 98%
Purification:: HPLC Purified
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 131740-09-5
Immunogen:: Kinase
Extra Details:: Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.