Leelamine HCl

Size

£149.00

SKU:: 10-2955
Additional Names:: (+)-Dehydroabietylamine HCl|Lylamine HCl
Physical State:: Solid
Molecular Weight:: 321.93
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 16496-99-4
Immunogen:: Cytochrome/MDR|Kinase|Lysosome
Extra Details:: A lysosomotropic, intracellular cholesterol transport inhibitor with potential chemotherapeutic activity. Induces cholesterol accumulation in lysosomal/endosomal cell compartments via inhibition of autophagic flux.1 Induces apoptosis in breast cancer2, melanoma3 and prostate cancer cells4. A selective inducer of cytochrome P450 2B.5 Inhibits pyruvate dehydrogenase kinase (PDK), IC50=9.5 uM.6