10-2904
Z-DEVD-FMK
Size
£206.00
- SKU:
- 10-2904
- Physical State:
- Lyophilized
- Molecular Weight:
- 668.67
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 210344-95-9
- Immunogen:
- Protease
- Extra Details:
- Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5
- Shipping Conditions:
- Ambient