Nicotinamide

Size

£119.00

SKU:: 10-2840
Additional Names:: NAM|Niacinamide|Nicotinic acid amide|Vitamin B3
Physical State:: Solid
Molecular Weight:: 122.13
Purity:: >99%
Purification:: HPLC Purified
Storage Conditions:: RT
Supplier:: Focus Biomolecules
CAS Number:: 98-92-0
Immunogen:: Energy production|Kinase|Protein deacetylase
Extra Details:: Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions.1 Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 uM)2, but is quickly converted to NAD+ in cells3. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation.4 Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs).5