10-2838
Obeticholic acid
Size
£149.00
- SKU:
- 10-2838
- Additional Names:
- 6-ECDCA|6-Ethylchenodeoxycholic acid
- Physical State:
- Solid
- Molecular Weight:
- 420.63
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 459789-99-2
- Immunogen:
- Transcription factor
- Extra Details:
- A novel cholic acid analog which acts as a potent and selective FXR agonist (EC50= 99 nM). Displays anticholeretic activity in a rat model of cholestasis.1 Promotes adipocyte differentiation and regulates adipose cell function.2 Normalizes insulin sensitivity in a rabbit model of metabolic syndrome.3 A potentially new therapeutic agent for management of non-alcoholic fatty liver disease4 and NASH5. Displays therapeutic benefit in patients with primary biliary cirrhosis.6 Active in vivo.
- Shipping Conditions:
- Ambient