10-2757
Muscone
Size
£158.00
- SKU:
- 10-2757
- Physical State:
- Oil
- Molecular Weight:
- 238.42
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 541-91-3
- Immunogen:
- Cytochrome/MDR|Inflammasome
- Extra Details:
- Muscone (541-91-3) is a macrocyclic ketone found naturally in a glandular secretion of the musk deer which acts at human odorant receptor OR5AN1 and is used in perfumes.1 It suppresses inflammatory responses and neuronal damage in various models including a rat model of cervical spondylotic myelopathy2 and relieves inflammatory pain acting via the NOX4/JAK2-STAT3 and NLRP3 inflammasome pathway3. In the cardiovascular system it alleviates myocardial ischemia-reperfusion injury4 and improves cardiac function in mice after myocardial infarction5 via enhancement of angiogenesis6.
- Shipping Conditions:
- Ambient