10-2689
Reserpine
Size
£149.00
- SKU:
- 10-2689
- Additional Names:
- NSC59272
- Physical State:
- Solid
- Molecular Weight:
- 608.68
- Purity:
- 98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 50-55-5
- Immunogen:
- Cytochrome/MDR|Monoamine transporter
- Extra Details:
- Indole alkaloid isolated from Rauwolfia serpentina which acts as a potent antihypertensive agent. Irreversibly inhibits both isoforms of vesicular monoamine transporter VMAT1 and 2, Ki=34 and 12 nM, respectively.1,2 May be used to pharmacologically deplete monoamines in various animal models.3 Inhibits the multidrug resistance protein P-glycoprotein, IC50=0.5 mM.3 Reserpine-induced hypokinesia is considered a useful animal model of Parkinson's disease.5
- Shipping Conditions:
- Ambient