Obatoclax

Size

£168.00

SKU:: 10-2660
Additional Names:: GX15-070
Physical State:: Solid
Molecular Weight:: 413.50
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 803712-79-0
Immunogen:: Bcl-2
Extra Details:: A novel Bcl-2 homology domain-3 (BH3) mimetic1. Inhibits primary acute myeloid leukemia (AML) progenitor cell proliferation (IC50=0.18 uM) and induces apoptosis in primary AML cells (IC50= 3.6 uM)2. Synergizes with other agents such as chloroquine3 and cytarabine4 in cytotoxicity against a variety of cancer cells.