10-2632
Migalastat
Size
£139.00
- SKU:
- 10-2632
- Additional Names:
- 1-deoxygalactonojirimycin|AT1001|DDIG|DGJ|GR181413
- Physical State:
- Solid
- Molecular Weight:
- 199.63
- Purity:
- >98%
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 75172-81-5
- Immunogen:
- Chaperone|Galactosidase
- Extra Details:
- Migalastat is a potent, selective, and orally available inhibitor of A Alpha-galactosidase A (IC50= 40 nM).1 It binds to mutant misfolded A Alpha-GalA shifting the folding behavior toward functional active conformation (pharmacological chaperone activity) followed by trafficking to the lysosomes.2 Migalastat is active broadly across species from Drosophila3 to human4. Clinically useful agent for Fabry disease.5
- Shipping Conditions:
- Ambient