10-2631
Triptolide
Size
£134.00
- SKU:
- 10-2631
- Additional Names:
- PG490
- Physical State:
- Solid
- Molecular Weight:
- 360.40
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 38748-32-2
- Immunogen:
- Transcription factor
- Extra Details:
- Possesses potent immunosuppressive and anti-inflammatory activity. Irreversibly inhibits eukaryotic transcription via covalent binding to XPB, a subunit of the transcription factor TFIIH.1 Blocks transactivation of NFK KappaB.2 Exhibits potent antiproliferative activity in 60 cancer cell lines (average IC50 = 12 nM) and synergizes with other anticancer agents.3 Inhibits the inflammatory response and remarkably decreases production of TNF-A Alpha, IL-1B Beta and IL-6 in a rat model of rheumatoid arthritis.4
- Shipping Conditions:
- Ambient