Monastrol

Size

£173.00

SKU:: 10-2629
Physical State:: Solid
Molecular Weight:: 292.35
Purity:: 98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 254753-54-3
Immunogen:: Cytoskeleton
Extra Details:: Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 uM).2 Mimics the effect of amyloid B Beta on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4