10-2626
Crizotinib
Size
£177.00
- SKU:
- 10-2626
- Additional Names:
- PF-02341066|PF-1066
- Physical State:
- Solid
- Molecular Weight:
- 450.34
- Purity:
- 98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 877399-52-5
- Immunogen:
- Kinase
- Extra Details:
- A potent and selective inhibitor of c-MET and ALK, IC50s=8 and 20 nM respectively.1 Inhibition of cell proliferation was associated with G1-S phase cell cycle arrest and induction of apoptosis in ALK-positive ALCL cells (IC50=30 nM) but not in ALK-negative lymphoma cells.1 Exhibits cytoreductive antitumor efficacy via antiproliferative and antiangiogenic mechanisms.2 Clinically useful anticancer agent.3
- Shipping Conditions:
- Ambient