10-2618
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Size
£129.00
- SKU:
- 10-2618
- Additional Names:
- Bisphenol A diglycidyl ether
- Physical State:
- Solid or oil
- Molecular Weight:
- 340.41
- Purity:
- 95%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 1675-54-3
- Immunogen:
- Transcription factor
- Extra Details:
- PPARG Gamma antagonist with uM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARD Delta and PPARA Alpha. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARG Gamma and abolishes its anti-inflammatory effects in a mouse model1. Induces apoptosis via PPARG Gamma-independent mechanisms2. Induces adipogenesis in human and mouse mesenchymal stromal stem cells and in mouse 3T3-L1 preadipocytes at low nM concentrations via a PPARG Gamma independent mechanism3. Increases osteoblastogenesis and bone mass in a mouse model4. Active in vivo.
- Shipping Conditions:
- Ambient