SB-3CT

Size

£177.00

SKU:: 10-2493
Physical State:: Solid
Molecular Weight:: 306.39
Purity:: >98%
Storage Conditions:: -20[o]C
Supplier:: Focus Biomolecules
CAS Number:: 292605-14-2
Immunogen:: Protease
Extra Details:: SB-3CT (292605-14-2) is a potent and selective inhibitor of MMP2 (Ki=28 nm) which also inhibits MMP9 (Ki=400 nM).1 The drug rescues laminin from proteolysis and neurons from apoptosis in a transient focal cerebral ischemia mouse model.2 It abrogates elevation of blood brain barrier (BBB) permeability in mouse Parkinson's disease models3 and improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease4. BBB permeable.