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10-2491

CUDC-101

Size

£168.00

SKU:
10-2491
Physical State:
Solid
Molecular Weight:
434.49
Purity:
99%
Purification:
HPLC Purified
Storage Conditions:
-20[o]C
Supplier:
Focus Biomolecules
CAS Number:
1012054-59-9
Immunogen:
Kinase|Protein deacetylase
Extra Details:
A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2
Shipping Conditions:
Ambient