10-2479
Topotecan HCl
Size
£141.00
- SKU:
- 10-2479
- Additional Names:
- NSC 609669|SKF-104864A
- Physical State:
- Solid
- Molecular Weight:
- 457.91
- Purity:
- >98%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 119413-54-6
- Immunogen:
- DNA|Topoisomerase
- Extra Details:
- Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN expression in neuroblastoma cells.3 A clinically useful anticancer agent.
- Shipping Conditions:
- Ambient