10-2424
Echinomycin
Size
£187.00
- SKU:
- 10-2424
- Additional Names:
- NSC-13502|Quinomycin A
- Physical State:
- Solid
- Molecular Weight:
- 1101.26
- Purity:
- >97%
- Purification:
- HPLC Purified
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- CAS Number:
- 512-64-1
- Immunogen:
- Antibiotic|Transcription factor
- Extra Details:
- Echinomycin is a potent and selective hypoxia inducible factor 1A Alpha (HIF-1A Alpha) inhibitor. It binds to DNA via bifunctional intercalation, blocking the interaction of HIF-1A Alpha.1 Protects mice against relapsed acute myeloid leukemia with no effect on hematopoietic stem cells.2 Selectively eliminates cancer stem cells in mouse lymphoma and human AML xenogeneic models.3 A very useful tool for probing genes regulated by HIF1A Alpha.4
- Shipping Conditions:
- Ambient